Biophysics of Dna-Protein Interactions: From Single Molecules to Biological Systems (Biological and Medical Physics)

Description

Introduction

Section 1. Nonspecific DNA binding: searching DNA and altering DNA properties

1. Mirny -DNA search theory

2. Yan Mei Wang-DNA search, hopping vs. sliding

3. Williams-SSB DNA search

4. Wuite-HN-S proteins or DNA sliding search

5. Barsky-processivity clamp

6. Maher-DNA bending proteins

7. Ansari- kinetics of DNA binding and bending by proteins

8. Record- modes of DNA interaction by architectural proteins

Section 2. Complex protein-DNA interactions

1. Finzi- DNA looping by repressor proteins

2. Ghosh - NF-kappaB transcription factor crystallography

2. van Oijen - Replication complex

3. Morrical - DNA recombination complexes

4. Fried- DNA binding by alkyltransferase repair proteins

5. Beese or Darst- DNA polymerase crystallography

6. Beuning - Polymerase switching in response to DNA damage

7. Leuba - single molecule studies on chromatin

8. Higgs- Regulation of chromosome conformation in cells

9. Widom- nucleosome positioning across genomes